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Go Medical is the first
company to appreciate the value of nasal patient controlled analgesia.
Using lipophilic drugs such as fentanyl and sufentanyl it is possible
to achieve the same level of pain management as intravenous PCA
as drugs delivered to the nasal mucosa act as quickly as intravenous
injections. The nasal route avoids hepatic first pass metalolism
that castly reduces the bioavilability of some oral medicatons.
The Go Medical nasal PCA device is a hand activated spray that is
higly acceptable to patients. It incorporates a 3 minute fill time
(during which another full dose cannot be delivered) and is suitable
for use with fentanyl, alfentanil and meperidine. The spray is delivred
in small droplet form, reducing the volume of drug reaching the
nasopharynx. Applications include pre-emptive analgesia (eg dressing
changes for patients with burns), moderate to severe pain in children
and adults and pallatice care.
Bottles can be ordered which deliver 9 micrograms of fentanyl with
7 micrograms being absorbed in 3 minutes combined with a 3 minute
lockout. (Maximum hourly dose absorbed: 140 micrograms)
The Future: This new method
of PCA is likely to replace intra-muscular injections in most hospitals
and to facilitate pain relief for outpatient and day surgery units.
 
Nasal Spray
Features:
- Portable.
- 0.18mL spray.
- 3, 4 or minute filling
time.
- 80μm droplet spray.
- Extremely simple to
use.
- Promotes patient moility.
- Reduces dependance on
nursing staff.
- As effective as IV PCA
- Suitable for fentanyl
and pethidine .
- Screw top and crimp
top models available. Screw top model can be refilled by pharmacist
- Safe, low cost and easy
to fill.
Can also be use with any
soluable lipophilic drug like fentanyl, alfentanyl, midazolam, sufentanyl,
oxycodone, pethidine, meperidine, butorphanol, buprenorphine and
lignocaine. (Note: occasionally pethidine or meperidine can cause
irritation to the nasal mucosa and give a bitter taste if swallowed
down the oropharynx. Suggestion: the patient sucks a lolly.)
Catalogue Number:
No Lockout Nasal Sprays
- NSS 000: No lockout
screw top.
Lockout Nasal Sprays
- NSC 030: 3 min lockout
crimp top.
- NSC 040: 4 min lockout
crimp top.
- NSC 050: 5 min lockout
crimp top.
- NSS 030: 3 min lockout
screw top.
- NSS 040: 4 min lockout
screw top.
- NSS 050: 5 min lockout
screw top.
Nasal Spray pouch
- NSP 02: Nasal spray
clip on pouch.
References:
- Schwagmeier et al. Pharmacokinetics of intranasal
Alfentanyl. Journal Of Clinical Anaesthesia 1995; 7:109-115
- Helmers etal. Comparison of Intravenous and intranasal
Sufentanyl Absorption. Canadian Journal of Anaesthesia 1989;36:494-7
- Striebel HW et al. Postoperative Pain Management
by Intranasal demand Adapted Fentanyl Titration. Anaesthesiology
1992; 77:281-5
- Striebel HW et al. intranasal Meperidine Titration
for Postoperative Pain Relief. Anaesthesia Analgesic 1993; 76:1047-51
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