Go Medical is the first company to appreciate the value of nasal patient controlled analgesia. Using lipophilic drugs such as fentanyl and sufentanyl it is possible to achieve the same level of pain management as intravenous PCA as drugs delivered to the nasal mucosa act as quickly as intravenous injections. The nasal route avoids hepatic first pass metalolism that castly reduces the bioavilability of some oral medicatons.

The Go Medical nasal PCA device is a hand activated spray that is higly acceptable to patients. It incorporates a 3 minute fill time (during which another full dose cannot be delivered) and is suitable for use with fentanyl, alfentanil and meperidine. The spray is delivred in small droplet form, reducing the volume of drug reaching the nasopharynx. Applications include pre-emptive analgesia (eg dressing changes for patients with burns), moderate to severe pain in children and adults and pallatice care.

Bottles can be ordered which deliver 9 micrograms of fentanyl with 7 micrograms being absorbed in 3 minutes combined with a 3 minute lockout. (Maximum hourly dose absorbed: 140 micrograms)

The Future: This new method of PCA is likely to replace intra-muscular injections in most hospitals and to facilitate pain relief for outpatient and day surgery units.

Nasal Spray Features:

• Portable.
• 0.18mL spray.
• 3, 4 or minute filling time.
• 80μm droplet spray.
• Extremely simple to use.
• Promotes patient moility.
• Reduces dependance on nursing staff.
• As effective as IV PCA
• Suitable for fentanyl and pethidine .
• Screw top and crimp top models available. Screw top model can be refilled by pharmacist
• Safe, low cost and easy to fill.

Can also be use with any soluable lipophilic drug like fentanyl, alfentanyl, midazolam, sufentanyl, oxycodone, pethidine, meperidine, butorphanol, buprenorphine and lignocaine. (Note: occasionally pethidine or meperidine can cause irritation to the nasal mucosa and give a bitter taste if swallowed down the oropharynx. Suggestion: the patient sucks a lolly.)

Catalogue Number:

No Lockout Nasal Sprays

• NSS 000: No lockout screw top.

Lockout Nasal Sprays

• NSC 030: 3 min lockout crimp top.
• NSC 040: 4 min lockout crimp top.
• NSC 050: 5 min lockout crimp top.
• NSS 030: 3 min lockout screw top.
• NSS 040: 4 min lockout screw top.
• NSS 050: 5 min lockout screw top.

Nasal Spray pouch

• NSP 02: Nasal spray clip on pouch.

References:

1. Schwagmeier et al. Pharmacokinetics of intranasal Alfentanyl. Journal Of Clinical Anaesthesia 1995; 7:109-115
2. Helmers etal. Comparison of Intravenous and intranasal Sufentanyl Absorption. Canadian Journal of Anaesthesia 1989;36:494-7
3. Striebel HW et al. Postoperative Pain Management by Intranasal demand Adapted Fentanyl Titration. Anaesthesiology 1992; 77:281-5
4. Striebel HW et al. intranasal Meperidine Titration for Postoperative Pain Relief. Anaesthesia Analgesic 1993; 76:1047-51